the net rich poor ratio is calculated as the absolute deviation of the odds ratio of the fifth quintile from unity
Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt
... the inactivity as an inhibitor of tPA and the resistance of the reactive loop to cleavage The lower portion of b-sheet A is filled by unfolding of the F-helix (yellow) Right, the F-helix is displaced ... rate of °CÆmin)1 at a concentration of 0.7 mgÆmL)1 The second derivative of the resulting data was used to calculate the inflection point of the transition and hence the Tm [14] Assessment of the ... In the case of Ser52Arg neuroserpin, the signal magnitude only allows us to calculate an approximation of the melting temperature (Tm) This gave a Tm of 55 °C This Tm was surprising as it is...
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Báo cáo khóa học: CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes doc
... activity of each of the mutants is given in parentheses It was determined by setting the Vmax adjusted activity of CD38-WT to 100% and then calculating the percentage activity of each of the mutants ... Each of the mutant CD38 cDNAs listed, was stably expressed in Ba/F3 cells and the enzyme activity (Vmax) of the membrane homogenates was determined as described previously [30] The Vmax was adjusted ... suggest that these domains are not obligate for the stabilization of the dimers, but rather must contribute to the overall stability of the dimers Crystallographic analysis of the Aplysia cyclase indicates...
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n order to better illustrate the necessary functions and features of this application, a rainwater retention basin is assumed as example
... PLC sem Watchdog [006] - Programas demo PLC S7-1200 da SIEMENS (Simatic) This configuration example CE-X25 helps to solve the tasks displayed The focus is on the library blocks which enable SMS-Sending ... for STEP Basic V11 Containing also the outdated library based on STEP V10.5 CE-X25_S7-1200_SM S_library.zip Configuration Example X25 (Documentation based on the Startup-Code) ConfigurationExampl ... SMS-Sending and SMS-Receiving Downloads Content of the downloads Download Library description on the Configuration Example X25 (Documentation for the implemented STEP V11 library) LibraryDescription_S...
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Báo cáo y học: "Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener’s granulomatosis" pptx
... without granulomas The only apparent issue the WG specimens have in common is the upregulation of PR-3 throughout the whole specimen The upregulation of PR-3 in the lung of WG patients may therefore ... endothelial cells This is in line with our recent findings of de novo synthesis of PR-3 in endothelial cells [24] On the contrary, most endothelial cells (even at multiple sites of acute vasculitis ... endothelial cells [13,14] The lung is the organ most frequently involved in WG, and in some cases it is the only organ affected [15] Given the potential importance of PR-3 in the pathogenesis of...
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Báo cáo sinh học: " Response to mass selection when the genotype by environment interaction is modelled as a linear reaction norm" pptx
... environment Mass selection with 10% of the males and 10% of the females selected was assumed The selection response is expressed in phenotypic SD-units of the trait expressed in the environment of the ... environment, the environmental variance of slope was increased so that heritability decreased with an increasing distance from the intercept, being 5% lower at SD from the intercept The Bulmer effect was ... increasing distance from the environment of the intercept With a non zero correlation between level and slope, the variance changed asymmetrically at the two sides of the environment of the intercept...
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performance of robust controller for dfim when the rotor angular speed is treated as a time-varying parameter
... variation of the rotor speed around the synchronous speed From that point, the deviation of the rotor speed by from the nominal speed can be expressed as (30) (31) (23) where is an unity matrix, is ... trajectory is given by the step response of the rotor speed Figures 13a,c,e show the behaviors of the and components of the rotor currents when the rotor angular speed increases from 70% to 130% of the ... speed of the rotor , where (rad/s), Conversely, the behaviors of the and components of the rotor currents when the rotor angular speed decreases from 130% down to 70% of the nominal speed of the...
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Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"
... Danish Work Environment Cohort Study (DWECS) and the national register on social transfer payments (DREAM) DREAM is a register based on data from the Danish Ministry of Employment, the Ministry ... where either disability pensioned, emigrated or died They were excluded from the study, as they were no longer under risk of disability pension in the follow-up period from 1994 through 2004 This ... days of absence per annum decreased from 2.77 to 2.68, and remained significant There was an increased risk of disability pension for people who were smokers at baseline, whereas there was no...
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Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... C677T polymorphism was associated with an increased risk of coronary heart disease [9,22] whereas others failed to demonstrate this association [23-25] Furthermore, a recent meta-analysis study pointed ... measurement of the vessel thickness Measurement of the CIT was Int J Med Sci 2004 1: 181-192 183 done at the far wall of the vessel 1cm proximal to its bifurcation Mean CIT was calculated as the ... illustrated the positive effect of folate intake on the reduction of plasma tHcy level and subsequent decrease in the incidence of cardiovascular diseases [46-49] In the present study there was no...
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The pursuit of the subject - literature as critic and perfecter of philosophy 1790-1830
... consciousness, the other the history of nature, each complementing the other in the story it tells This division of labour, based on the conception of an autonomous realm of nature distinct from the transcendental ... at the price of the total rejection of conscious thinking, but it is also the beginning of the discovery of the unconscious mind The first sign of decay in the utopian aesthetic consensus is the ... bathes in the wellsprings of creation, the menstruum universale of the cosmic imagination Here, mere thinking is creation of self and other This phase of the dream, then, is a literary figuration...
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Comparison of the obstetric anesthesia activity index with total delivery numbers as a single denominator of workload demand in Israeli maternity units doc
... it is obvious that coupling exists, as the OAAI is derived from both epidural rates and cesarean rates, it is precisely for this reason that this single denominator is a more reliable measure of ... experience of personnel Accordingly, the OAAI is not a measure of the total activity of the obstetric anesthesia services Based on these limitations, it is important to appreciate that although the ... numbers of deliveries, epidurals, and cesareans annually, together with the anesthesia workforce allocated for the provision of obstetric anesthesia services The OAAI was calculated based on the...
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Báo cáo khoa học: Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis docx
... exchange factor for Ran Conversely, the concentration of RanGDP is high in the cytoplasm as a result of the action of RanGAP, which promotes cytoplasmic GTP hydrolysis by Ran in conjunction with RanBP1 ... represent the SEM analyzed As shown in Fig 2A, the protein level of Nup358, a component of the cytoplasmic filaments of the NPC, gradually increased as muscle cell differentiation proceeded All other ... formation, whereas the outer diameter and the height of the NPC were not significantly changed Thus, the shape of the NPCs in myoblasts differs from that in myotubes Nup358 is a cytoplasmically exposed...
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Báo cáo khoa học: The Rieske protein from Paracoccus denitrificans is inserted into the cytoplasmic membrane by the twin-arginine translocase doc
... [2Fe)2S] cluster of the Rieske protein is inserted in the cytoplasm As cytosolic cofactor insertion is one of the hallmarks of Tat translocation, the cofactor loading status of the ISP in P denitrificans ... activity of the enzyme; this seems plausible as the structures of mitochondrial homologues show that the N-terminal part of the ISP is far from the catalytic centres and is separated by the membrane ... motif However, as in the case of the thylakoid ISP and in contrast to the majority of other Tat substrates, transport of the P denitrificans ISP shows more relaxed requirements regarding the conserved...
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Báo cáo khoa học: Identification of NF1 as a silencer protein of the human adenine nucleotide translocase-2 gene pptx
... used as positive and negative PCR controls As a marker (lane M), the 100-bp gene ruler (Fermentas) was used isoforms Furthermore, NF1 exist in the cell as homodimers or heterodimers [25], and the ... affinity is the last step in the purification scheme Footprinting activity is eluted from the DNA affinity column only in fractions and of the low salt (200 mM NaCl) wash (Fig 2B) SDS/PAGE analysis revealed ... protein as a member of the NF1 family of transcription factors (A) Binding of purified, recombinant NF1 to the Site-2 and Site-3 elements was monitored by the DNase I protection assay of ANT2...
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Báo cáo khoa học: Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines docx
... of Tyr1138 in these assays, as the mutation of Tyr1138 enhanced luciferase activity (YYF vs WT, P < 0.001, double-sided t-test) This result is consistent with the known requirement of Tyr1138 for ... et al The aim of this study was to analyse the contribution of the intracellular tyrosine residues to LEPRbmediated effects on STAT factors, MAP kinase and AMPK These data show that LEPRb is capable ... (spi2.1) The bottom panel of Fig provides an expression control for the different LEPR mutants as aliquots of the same DNA samples were transfected in this experiment Structural basis for the recruitment...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... (PDE5A) and increased cGMP degradation [24] On desensitization, there was a decrease in the Vmax of the guanylyl cyclase catalytic activity of GC-C with no change in the S0.5 of the enzyme for ... level over the time period of the experiments as conducted here As shown below, alterations in the levels of the differentially glycosylated forms of GC-C regulate the cellular response to the ST-peptide, ... As shown in Fig 4D, swainsonine inhibited the reacquisition of responsiveness by 50% This shows that modification of the a-1,6 arm of the mannose residues was essential to allow formation of the...
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As I Remember Recollections of American Society during the Nineteenth Century docx
... good graces of the English throne, and it was Scotland that was compelled to bear the brunt of the royal displeasure The sins of the fathers were visited upon their children, and it is not at all ... Sarah Morris, the granddaughter of Lewis Morris, the Signer, and the mother of the senior Mrs Hamilton Fish A younger sister of Mrs Fish, Christine, who many years later was a pupil of Madame ... removal of my father from office, and he immediately resumed the practice of law Some of his decisions as Surrogate are regarded as precedents to this day Two of the most prominent of these are...
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Báo cáo khoa học: Identification of mitogen-activated protein⁄extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-large docx
... functions [2] The outcomes of ERK activation are as various as the ERK substrates, and so an accurate regulation of the ERK signaling pathway is necessary This pathway is under the control of different ... oriented migration Previews studies performed on various tissues outside the vascular system, including the brain, liver and heart, have initially revealed the existence of several isoforms of the hDlg ... example, the phosphoprotein enriched in astrocyte-15 binds ERK1 ⁄ and ribosomal protein S6 kinase 2, a direct substrate of ERK, thereby enhancing the activation of this latter kinase [6] Human disc-large...
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Báo cáo khoa học: Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases pot
... substrate the RNase H activity was measured as described [20,39] The RDDP activity of HIV-1 RT was measured as described previously [40] Kinetic studies Analysis of the kinetics of inhibition was performed ... toward the RNase H catalytic site According to this mechanism, the AQs inhibit the RT-associated RNase H by avoiding the correct anchorage of the primer grip to the nucleic acid, whereas they inhibit ... on the wild-type RT RDDP activity using the YonetaniTheorell plot [25] The results showed that when the HIV-1 RT RDDP activity was measured in the presence of increasing concentrations of one of...
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Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... proteases, the activation of caspase being transient and the activation of caspase being stronger and sustained over time In addition, the length of activation of caspase is similar to the time ... because some caspase substrates are also cleaved by other caspases, typically caspase 3, at other cleavage sites [22] Further work is required to establish the identity of the caspase responsible ... either stimulus These results show that the loss of hDlg over the time course of sorbitol or UV treatment (Fig 1C,D) correlated with the kinetics of caspase activation, particularly of caspase...
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Báo cáo khoa học: An intermediate step in the evolution of ATPases ) the F1F0-ATPase from Acetobacterium woodii contains F-type and V-type rotor subunits and is capable of ATP synthesis Michael Fritz and Volker Muller ¨ docx
... of V1V0ATPases has only half the number of ion-binding sites This is seen as the reason for the apparent inability of V1V0-ATPases to catalyze ATP synthesis in vivo Indeed, V1V0-ATPases have ... of 70% of the activity (Table 1) The molecular mass of the complex as determined by gel filtration was 590 kDa As can be seen from Fig 1, the enzyme preparation contained 12 polypeptides The identity ... indistinguishable from those of the preparation described previously [25] Characterization of the Na+ F1F0-ATP synthase from A woodii The specific ATPase activity of the complete enzyme was in the range 5–9.9...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25